Abstract: Nickel-based single crystal superalloys have excellent mechanical properties at high temperature and are key materials in the aerospace and nuclear fields. The γ channel evolution of the third-generation nickel-based single crystal superalloy DD10 was investigated by examining the changes in the as-cast, force loaded, and heat-treated states. The single crystal properties of the as-cast sample were also tested using four-circle neutron diffraction. The results show that DD10 has good single crystal properties on the 200, 020 and 002 crystal faces. The ordering of the γ matrix channels and the channel width increase after force loading and heat treatment, and secondary precipitates strengthen the γ matrix channels under loading. After heat treatment at 900 ℃, the Co and Cr element contents in the γ matrix channels significantly increase,and the Co element content is consistent in the same vertical channels. The Cr element content is consistent in the same horizontal channels. Trace elements such as Mo, Re, and W enter more into the precipitation-strengthened phase from the γmatrix channels after heat treatment.