Abstract: Fe-Cr-Mo-Ni-B cladding was prepared by plasma cladding technology. The effects of cladding current, powder feeding rate and cladding speed on the microstructure and properties were studied by orthogonal test. The effects of multichannel cladding and preheating conditions on the morphology, microstructure and properties of the cladding layer were further explored. The results show that the process parameters have obvious influence on the size, morphology and distribution of boride precipitation in the cladding layer. Under the conditions of plasma cladding current 100 A, cladding speed 3 mm/s and powder feeding rate 8.5 g/min, the cladding layer with good formability can be obtained. The microstructure of the cladding layer is composed of Mo₂FeB₂, binary eutectic structure and Fe（Ni, Cr） matrix. The hardness of the cladding layer decreases with the increase of preheating temperature and wear resistance decreases.