Abstract: Al_0.1CoCrFeNiV_0.4 alloy was prepared by arc melting and subsequently examined in its as-cast state and after different heat treatments by using XRD, SEM, Vickers hardness, and tensile tests. It is found that the cast sample of the alloy is a structural homogeneity and single FCC phase solid solution. The application of heat treatment results in a phase transformation of the alloy. At temperatures exceeding 800 ℃, a portion of the FCC phase matrix undergo a structural change to a BCC phase structure. As the duration of the heat treatment is extended, the precipitation and subsequent disappearance of the BCC phase occurs in a successive manner within the alloy. The hardness, tensile yield strength, and compressive yield strength of the alloys demonstrate a general trend of initial increase followed by subsequent decrease with theincrease of heat treatment temperature and duration. This trend is approximately parallel to that of the content of the BCC phase. The tensile fracture morphology of the alloy exhibits a transition from toughness to brittle fracture and subsequently to ductile fracture with an increase in heat treatment temperature and duration. The alloy exhibits the highest yield strength,tensile ultimate strength, strain hardening rate, hardness, and compressive strain hardening rate at low strain following heat treatment at 900 ℃-6 h. Therefore, 900 ℃-6 h is the optimal heat treatment process for this alloy.